Wesley George Tyree of O'Fallon, MO passed away on May 29, 2025 at the age of 68. He is survived by his beloved wife, Cynthia Tyree (nee Simon) of O'Fallon, Missouri; his two daughters, Tamara (Patrick) Favazza and Lauren (Nicholas Zvorak) Tyree; brother, Thomas (Christy) Tyree; grandchildren, Ava, Giada, Vincent, Francesca, Milana, and Zachary; two nieces, Brittany (Tim) Ransom and Lindsay (Dr. Adam) Madej; great-nephews, Collin and Jack; and stepmother, Sherry Tyree. He is preceded in death by his father, Dr. Donald Tyree, mother, Dr. Carolyn Tyree (nee Lucy), and stepbrother, Paul Tyree.  

Wesley was a devoted parishioner of St. Gianna Catholic Church. His life was a testament to his unwavering faith in God. He found great joy in the outdoors, especially while fishing, boating, and camping. A talented keyboard player and a passionate Texas Longhorns fan, Wesley brought enthusiasm to everything he did. Above all, he cherished time spent with his family. His warmth, spirit, and presence will be deeply missed by all who knew and loved him.

In lieu of flowers, memorial donations may be made to: Masses or St. Vincent DePaul at St. Gianna Catholic Church. 

The family is being served by Pitman Funeral Home in Wentzville, MO